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Antioxidants
Resveratrol
Also known as: Trans-resveratrol · RSV
Emerging Evidence127+ human studies
A polyphenol that activates sirtuins (SIRT1). Famous from David Sinclair's research. Human data more mixed than animal studies.
Mechanism of Action
Activates SIRT1 and AMPK. Mimics some effects of caloric restriction. Anti-inflammatory via NF-κB inhibition.
Dosage & Timing
Dose
500mg–1g/day
When to take
With a fatty meal for absorption
Caution
May interact with: blood-thinners
Evidence Scores
Evidence Quality
C0/100
Safety Profile
A0/100
Popularity
A0/100